Rfam COVID-19 Resources
In response to the SARS-CoV-2 outbreak,
Rfam produced a special release 14.2
that includes new and updated Coronavirus families.
Read more in a blog post
or download the data
Coronavirus UTR families
Untranslated regions (UTR) are important functional elements that have
conserved secondary structure and are responsible for multiple functions,
including replication and packaging.
The following new families represent the 5'- and 3'-UTRs
of the Coronavirus genomes:
- Alphacoronavirus 5'-UTR RF03116
- Alphacoronavirus 3'-UTR RF03121
- Betacoronavirus 5'-UTR RF03117
- Betacoronavirus 3'-UTR RF03122
- Sarbecovirus 5'-UTR RF03120
- Sarbecovirus 3'-UTR RF03125
- Gammacoronavirus 5'-UTR RF03118
- Gammacoronavirus 3'-UTR RF03123
- Deltacoronavirus 5'-UTR RF03119
- Deltacoronavirus 3'-UTR RF03124
Non-UTR Coronavirus RNAs
The following Coronavirus families have been updated to expand the seed alignments:
- Coronavirus packaging signal RF00182
- Coronavirus s2m RNA RF00164
- Coronavirus 3'-UTR pseudoknot RF00165
- Coronavirus frameshifting stimulation element RF00507
Acknowledgements
We would like to thank Kevin Lamkiewicz and Manja Marz (Friedrich Schiller University Jena) for providing the curated UTR alignments as well as Eric Nawrocki (NCBI) for revising the existing Rfam entries.
Where do I find more data?
More data on SARS-CoV-2 can be found on the European COVID-19 Data Portal, which brings together all relevant datasets submitted to EMBL-EBI and other major centres for biomedical information.
Learn about other viral RNA families in Rfam →
