{"rfam": {"acc": "RF03121", "id": "aCoV-3UTR", "description": "Alphacoronavirus 3'UTR", "comment": "The 3' UTR of alphacoronaviruses consists of two small hairpins (PK-SL2) which can form an alternate conformation (PK-SL1) where the loop region of the second hairpin interacts with the stem of the first hairpin. PK-SL2 has been confirmed in HCoV-229E and HCoV-NL63 by in vitro structure probing experiments. Downstream of this pseudoknot lies the hypervariable region (HVR), which is supported by many covarying basepairs in alphacoronaviruses. Further, a conserved octanucleotide sequence is present in the HVR.", "curation": {"author": "Lamkiewicz K", "seed_source": "Kevin Lamkiewicz", "num_seed": 17, "num_full": 29, "num_species": 35, "type": "Cis-reg;", "structure_source": "Predicted;"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 85.0, "trusted": 87.2, "noise": 84.7}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00117", "id": "Coronavirus-3UTR"}}}