Rfam 14.10 (November 2023, 4170 families)

The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models

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Getting started

Sequence search

Annotate your sequences with RNA families and visualise their secondary structure using R2DT

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Download covariance models, FASTA sequences, database dumps, previous releases, and more

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Access Rfam using the API and public MySQL database, or learn how to annotate genomes using Infernal

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Citing Rfam

If you use Rfam, please cite our latest papers:

Rfam 14: expanded coverage of metagenomic, viral and microRNA families
Kalvari et al., Nucleic Acids Research (2020)

Non-coding RNA analysis using the Rfam database.
Kalvari et al., Current Protocols in Bioinformatics (2018)
View all Rfam papers

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