{"rfam": {"acc": "RF00173", "id": "Hairpin", "description": "Hairpin ribozyme", "comment": "The hairpin ribozyme, like the hammerhead (RFAM:RF00008 and RFAM:RF00163), is found in RNA satellites of plant viruses. It was first identified in the minus strand of the tobacco ringspot virus (TRSV) satellite RNA where it catalyses a self-cleavage reaction to process the products of rolling circle virus replication to unit-length satellite RNA. The structure consists of 2 domains, A and B. The 3' arm of domain A, which closes helices 1 and 2, contains the cleavage site and is linked to helix 3 of domain B by a linker of variable length and sequence. This region is thus not included in this family. The hairpin ribozyme has been identified in only 3 plant satellite RNAs -- from TRSV, chicory yellow mottle virus (CYMV) and arabis mosaic virus (ARMV).", "curation": {"author": "Ditzler M", "seed_source": "Ditzler M", "num_seed": 5, "num_full": 0, "num_species": 4, "type": "Gene; ribozyme;", "structure_source": "Published; PMID:7966321"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 25.92 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 65.0, "trusted": 73.3, "noise": 39.7}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}