{"rfam": {"acc": "RF02885", "id": "SAM_VI", "description": "SAM-VI (S-adenosyl methionine) riboswitch aptamer", "comment": "sixth member of the riboswitch family predominantly found in Bifidobacterium and exhibits some similarities to the SAM-III (Smk box) riboswitch class, but it lacks most of the highly-conserved nucleotides of SAM-III class. SAM-VI aptamers bind the cofactor S-adenosylmethinine SAM (a key metabolite in sulphur metabolism) and discriminate strongly against S-adenosylhomocysteine SAH. The class was discovered by further analysis of Bifido-meK motif RNAs[1].", "curation": {"author": "Argasinska J", "seed_source": "Argasinska J", "num_seed": 7, "num_full": 12, "num_species": 19, "type": "Cis-reg; riboswitch;", "structure_source": "Predicted; RNAfold;"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 57.5, "trusted": 62.3, "noise": 57.1}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}