{"rfam": {"acc": "RF02877", "id": "NmsRb", "description": "Neisseria metabolic switch regulator b (RcoF1/NgncR163)", "comment": "Sibling sRNA described and independently named in three publications. NgncR163 is N. gonorrhoeae while the others are N. meningitidis RNAs. RcoF1 stands for: RNA regulating colonization factor 1. NmsRb_RcoF1_NgncR163 was shown to be the predominant sibling. They are tandemly arranged, structurally nearly identical and and share 70% sequence identity. They translationally down-regulate genes involved in basic metabolic processes including tricarboxylic acid cycle enzymes and amino acid uptake and degradation. The targets include: fumC, sdhC, gltA, sucC, prpB and prpC [1][3] Their expression is under the control of RelA.[3] Furthermore, they interact with Hfq and target mRNA that encodes putative colonization factor of the human nasopharynx (PrpB).[2] ", "curation": {"author": "Argasinska J", "seed_source": "Argasinska J", "num_seed": 6, "num_full": 65, "num_species": 50, "type": "Gene; sRNA;", "structure_source": "Predicted; RNAfold;"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 52.0, "trusted": 52.5, "noise": 51.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}