{"rfam": {"acc": "RF01854", "id": "Bacteria_large_SRP", "description": "Bacterial large signal recognition particle RNA", "comment": "The signal recognition particle (SRP) is a universally conserved ribonucleoprotein involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA (RFAM:RF00017) and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. In most bacteria, the SRP consists of a 4.5S RNA and the Ffh protein (a homologue of the eukaryotic SRP54 protein). Some Gram-positive bacteria (e.g. Bacillus subtilis) have a longer eukaryote-like SRP RNA that includes an Alu domain [2]. The Alu domain of the longer SRP RNAs is not included in this model and therefore the reported bounds of some members are incorrect. The Signal Recognition Particle Database (SRPDB) [1] provides compilations of SRP components, with phylogenetic data and structural illustrations.", "curation": {"author": "Gardner PP", "seed_source": "Published; PMID:19838050", "num_seed": 92, "num_full": 1447, "num_species": 1469, "type": "Gene;", "structure_source": "Published; PMID:19838050"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 28.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 60.0, "trusted": 60.0, "noise": 59.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00003", "id": "SRP"}}}