{"rfam": {"acc": "RF01054", "id": "preQ1-II", "description": "PreQ1-II (pre queuosine) riboswitch aptamer", "comment": "preQ1-II riboswitch was first reported for Weinberg et al. 2007 [7] it was recognised in Streptococcaceae and Lactococcus families in 5' untranslated regions of genes of a membrane protein classified as COG4708 or DUF988. Meyers et al. 2008 [1] confirm that preQ1-II recognise the queuosine (Q) precursor pre-queuosine 1 (preQ1). Q is a hyper modified nucleoside present in some anticodons in tRNAs (Try, Asn, Asp and His). The structure of preQ1-II riboswitch has been reported by Kang et al. 2014 [3], as preQ1 riboswitch (RF00522) preQ1-II structure present an unusual H-type pseudoknot featuring and differs in the interactions that recognise preQ1. The structure of preQ1-II riboswitch was reported in PDB:2MIY [3]", "curation": {"author": "Weinberg Z, Gardner PP, Ontiveros-Palacios N", "seed_source": "Published; PMID:18305186; Weinberg Z, Meyer MM, Gardner PP", "num_seed": 15, "num_full": 49, "num_species": 64, "type": "Cis-reg; riboswitch;", "structure_source": "Published; PMID:18305186; Gardner PP"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 47.0, "trusted": 47.0, "noise": 42.7}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}