{"rfam": {"acc": "RF00549", "id": "IRES_c-sis", "description": "c-sis internal ribosome entry site (IRES)", "comment": "This family represents the c-sis 5'-UTR which contains three modules that can individually mediate internal ribosome entry. However, the full length sequence is required for maximal IRES activity. It is thought that the three IRES elements are somehow responsive to cellular changes and act to regulate the level of translation [1].", "curation": {"author": "Moxon SJ", "seed_source": "Published; 10409733", "num_seed": 10, "num_full": 123, "num_species": 119, "type": "Cis-reg; IRES;", "structure_source": "Predicted; ILM; Moxon SJ"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 22.32 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 31.0, "trusted": 35.2, "noise": 24.0}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}