{"rfam": {"acc": "RF00462", "id": "IRES_APC", "description": "APC internal ribosome entry site (IRES)", "comment": "This family represents an APC internal ribosome entry site (IRES) which is located in the coding sequence of the gene. APC is a tumour suppressor gene which is associated with the inherited disease adenomatous polyposis coli (APC).It is thought that IRES-mediated translation of APC is important for an apoptotic cascade [1].", "curation": {"author": "Moxon SJ", "seed_source": "Published; 12034871", "num_seed": 6, "num_full": 6, "num_species": 9, "type": "Cis-reg; IRES;", "structure_source": "Published; PMID:12034871"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 21.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 50.0, "trusted": 52.9, "noise": 45.8}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}