{"rfam": {"acc": "RF00224", "id": "IRES_FGF2", "description": "FGF-2 internal ribosome entry site (IRES)", "comment": "This family represents the fibroblast growth factor 2 (FGF-2) internal ribosome entry site (IRES). When expressed the FGF-2 protein plays a pivotal role in cell proliferation, differentiation and survival as well as being involved in wound-healing [1,2]. It has been found that FGF-2 IRES activity is strictly controlled and highly tissue specific. It is thought that translational IRES dependent activation of FGF-2 plays a vital role in embryogenesis and in the adult brain [1].", "curation": {"author": "Moxon SJ", "seed_source": "http://ifr31w3.toulouse.inserm.fr/IRESdatabase/, INFERNAL", "num_seed": 6, "num_full": 95, "num_species": 84, "type": "Cis-reg; IRES;", "structure_source": "Predicted; PFOLD"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 25.81 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 35.0, "trusted": 35.8, "noise": 34.4}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}