# STOCKHOLM 1.0
#=GF ID mir-2
#=GF AC RF00047
#=GF DE mir-2 microRNA precursor family
#=GF AU Daub J; 0000-0001-6022-563X
#=GF GA 45.5
#=GF NC 45.4
#=GF TC 45.5
#=GF SE Griffiths-Jones SR
#=GF SS Predicted; PFOLD
#=GF TP Gene; miRNA;
#=GF BM cmbuild -F CM SEED
#=GF CB cmcalibrate --mpi CM
#=GF SM cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB
#=GF DR MIPF; MIPF0000049;
#=GF DR SO; 0001244; pre_miRNA;
#=GF DR GO; 0035195; miRNA-mediated post-transcriptional gene silencing;
#=GF DR GO; 0016442; RISC complex;
#=GF RN [1]
#=GF RM 11679672
#=GF RT An extensive class of small RNAs in Caenorhabditis elegans.
#=GF RA Lee RC, Ambros V
#=GF RL Science 2001;294:862-864.
#=GF RN [2]
#=GF RM 11779458
#=GF RT microRNAs: tiny regulators with great potential.
#=GF RA Ambros V
#=GF RL Cell 2001;107:823-826.
#=GF CC This family represents the microRNA (miRNA) precursors mir-2 and mir-13
#=GF CC (MIPF:MIPF0000049). mir-2 has now been predicted or experimentally
#=GF CC confirmed in a wide range of species. The miRNAs are transcribed as ~70nt
#=GF CC precursors (modelled here) and subsequently processed by the Dicer enzyme
#=GF CC to give a ~22nt product. In this case the mature sequence comes from the
#=GF CC 3' arm of the precursor. The extents of the hairpin precursors are not
#=GF CC generally known and are estimated based on hairpin prediction. The
#=GF CC products are thought to have regulatory roles through complementarity to
#=GF CC mRNA. The involvement of Dicer in miRNA processing suggests a relationship
#=GF CC with the phenomenon of RNA interference. miRNAs are numbered based on the
#=GF CC mature sequence. This family also contains the mir-13 precursor which,
#=GF CC despite giving rise to a distinct mature sequence appears to be related in
#=GF CC sequence.
#=GF WK mir-2_microRNA_precursor
#=GF SQ 56

AC007769.3/76981-76908           AAUGUCAUCAAAAAGGG-CU-GAAGAAA--GAUA---UUUCUGCAUU-----UGAAUCGUAUCACAGCCAGCUUUGAUGGGCAUUG
AC007769.3/76625-76559           CAUGUCGUUAAAA-UGU-UU-G-UGAACU-UAU--------GUAUUC-----ACAAUCAUAUCACAGCCA-UUUUGACGAGUUUGG
AC023719.4/66771-66704           UAACGCGUCAAAA-UGA-CU-G-UGAGC--UAUG---UGGAUUUG--------ACUUCAUAUCACAGCCA-UUUUGACGAGUUUGU
Z83731.1/29638-29566             AAAGCCAUCAAAG-CGG-UG-GUUGAUG--UGUU---GCAAAUUAUG-----ACUUUCAUAUCACAGCCAGCUUUGAUGUGCUGCC
AC092220.1/147044-147112         ACUGUCUUCAAAG-UGG-CA-G-UGACA--UGUU---GUCAACAA--------UAUUCAUAUCACAGCCAGCUUUGAGGAGCGUUG
AC005128.1/19054-19128           UCAUUCUUCAAAG-UGG-UU-G-UGAAA--UGUU---UGCCUUUUUAUGC--CUAUUCAUAUCACAGCCAGCUUUGAGGAGCGACG
AAIZ01000548.1/11193-11126       CAUGUCGUUAAAA-UGU-UU-G-UGACCU-UAUG---U----ACUCU-----UGAAUCAUAUCACAGCCA-UUUUGACGAGUUUGG
AAAB01008807.1/11606679-11606749 CAGGUCGUAAAAA-UGG-UU-G-UGCCG--UGUC---GAUUUAAGAA-----AAGUUCAUAUCACAGCCA-UUUUGACGAGUUUGA
AAZO01007079.1/41194-41254       CCACUCA-CAAAG-UGG-CU-G-GGGUA--UGUU---G---------------AAUUCAUAUCACAGCCAGCUUUGAUGAGCGGGA
AADK01013541.1/4027-3962         GAUCCUGUCAAAG-CGG-CG-G-UGAAA--UGU--------CUCCUC-----CCUUUCAUAUCACAGCCA-CUUUGAUGUGGUCGG
AADE01000834.1/22052-21985       UAACCCAUCAAA--CGG-UU-G-UGAAA--UGUU---GCAUUUAU-------CAAAUCAUAUCACAGCCA-UUUUGAUGAGUUUCG
AAIZ01000548.1/11570-11497       AGUGUCAUCAAAAAUGG-CU-GAAGAAA--GAUA---UAUUUGCAUU-----UGAAGCGUAUCACAGCCAGCUUUGAUGGGCAUUG
AAGH01000244.1/1102-1034         UAACUCCUCAAAG--GG-UU-G-UGAAA--UGUC---GACUAUUA-U-----CUACUCAUAUCACAGCCA-UUUUGAUGAGUUUCG
AAPU01010520.1/77495-77569       UGAGCUCUCAAAG-AGG-CU-G-UGAAA--UGCAUUUUGAAAGCUUU-----GCGAGCAUAUCACAGCCAGCUUUGAUGAGCUUAG
AANI01013749.1/162155-162082     UGCGCUCUCAAAG-UGG-UU-G-UGAAAUGCAUU---UGAAAGCUUU-----GCGCGCAUAUCACAGCCAGCUUUGAUGAGCUUAG
AANI01017189.1/98316-98382       CAUGUCGUUAAAA-UGC-CU-G-UGACCU-UAU--------GUAUUU-----UAUAUCAUAUCACAGCCA-UUUUGACGAGUUUGG
BAAB01090954.1/2653-2589         CCACUCGUAAAAA-UGG-CU-G-UGUCG--UGUA---G-------CA-----ACCCUCAUAUCACAGCCAUUUUUGACGAGUUGGG
AAGE02012793.1/16205-16139       AGACUC-UCAAAG-UGG-CU-G-UGAAA--UGGU---U----UUAUU-----UUGCUCAUAUCACAGCCAGCUUUGAUGAGCUGGA
AAPU01011022.1/363976-364043     UAACUCUUCAAGG--GG-UU-G-UGAAA--UGUA---GCCAUUAU-------CAAGUCAUAUCACAGCCA-UUUUGAUGAGUUUCG
AASU01000880.1/461-389           UGGGCUCUCAAAG-UGG-UU-G-UGAAA--UGCA---UUUCCGCUUUG----CGCGGCAUAUCACAGCCAGCUUUGAUGAGCUUAG
AAZX01013101.1/18721-18788       CCGAUCGUCAAAU-UGG-UU-G-UGGCG--UGUU---G----UCUAG-----AUUUUCAUAUCACAGCCAUUUUUGACGAGUUGGA
AAGE02012793.1/17697-17627       CGGAUCGUAAAAA-UGG-UU-G-UGCUG--UGUU---GUUACGCUCG-----AAAUUCAUAUCACAGCCA-UUUUGACGAGUUCGA
AAIZ01000971.1/3321-3388         ACGCUCUUUAAAG-UGG-CG-G-UGACG--UGUU---GGUAAUAA--------UAUUCAUAUCACAGCCAGCUUUGA-GAGCGUUG
AAWU01020422.1/10643-10573       CCACUC-UCAAAG-UGG-CU-G-UGAAA--UGGU---UCCUCCAGAA-----AUCGCCAUAUCACAGCCAGCUUUGAAGAGCGAUA
AAWU01020422.1/10370-10299       AGACUCA-CAAAG-UGG-CA-G-UGAAA--UGGU---ACUGUGUUUGA----UAUCGCAUAUCACAGCCAGCUUUGAUGAGCUGGA
AAQB01006412.1/121627-121699     GAGCUCA-CAAAG-UGG-UU-G-UGAAAUGCAUU---AUUUGCUUUA-----UCCAGCAUAUCACAGCCAGCUUUGAUGAGCUCUG
AANI01016575.1/52926-52998       UGGCGCGUCAAAA-UGA-CU-G-UGAGCUAUGUU---GUUGCAUUUG-----CCAUUCAUAUCACAGCCA-UUUUGACGAGUUUGA
AAIZ01004769.1/8926-8993         UUACGCGUCAAAA-UGA-CU-G-UGAGC--UAU------GUGUUUUU-----GAUCUCAUAUCACAGCCA-UUUUGACGAGUUUGA
AAPT01019328.1/229098-229026     AAUGUCAUCAAAAAGGG-CU-G-AGAAU--GAUA---UAUCUGCAAU-----UGAAUCGUAUCACAGCCAGCUUUGAUGGGCAUUG
AAQA01003088.1/958-1028          CGACACGUCAAAG-UGGUCA-G-UGAUG--UGUC---GCAAAAUG-------AAAUUCAUAUCACAGCCAGCUUUGAUGUGUUGUG
AAPU01010520.1/76994-77067       UCAUUCUUCAAAG-UGG-UU-G-UGAAA--UGUU---UGCUUUUUCUGC---CUACUCAUAUCACAGCCAGCUUUGAGGAGCGACA
AAJJ01001714.1/2416-2480         CAAGUCGUCAAUU-UGG-UU-G-UGAAC--UCU---------UAAUU-----UAAACGAUAUCACAGCCA-CUUUGAUGAGCUUGG
AAQB01008610.1/296847-296776     UAACUCUUCAAGG-GGG-UU-G-UGAAA--UGUU---GCCAUUUUAUU----CAACUCAUAUCACAGCCA-UUUUGAUGAGUUUCG
AAEU02000279.1/215063-215137     UCAUUCUUCAAAG-UGG-UU-G-UGAAA--UGUU---UGCCUUUUUCUGC--CUAUUCAUAUCACAGCCAGCUUUGAGGAGCGACG
AAAB01008807.1/11607145-11607220 UGUCUC-UCAAAG-UGG-CU-G-UGAAA--UGGU---GCACUUUCGAUCCGAUAUCUCAUAUCACAGCCAGCUUUGAUGAGCUAGG
AAPT01021140.1/8903-8975         UGGCGCGUCAAAU-UGA-CU-G-UGAGCUAUGUU---GUUGCAGUUG-----UAAUUCAUAUCACAGCCA-UUUUGACGAGUUUGA
AAQB01006881.1/26688-26760       GGUCGCGUCAAAA-UGA-CU-G-UGAGC--UAUG---UUAACCGGUCAG---AAAUUCAUAUCACAGCCA-UUUUGACGAGUUCGA
AAPU01011022.1/363722-363794     AGUGUCAUCAAAAAGGG-CU-G-AGAAU--GAUA---UUUCUGUAAU-----UGAAUUGUAUCACAGCCAGCUUUGAUGGGCACUG
AAQB01008610.1/296699-296630     CAUGUCGUUAAAA-UGU-UU-G-UGACUU-UAUG---UUGUGUCU-------CUAUUCAUAUCACAGCCA-UUUUGACGAGUUUGG
AAPP01015718.1/156815-156885     GGGCUCA-CAAAG-UGG-UU-G-UGAAA--UGCA---UUUCCAUUUU-----GCCCGCAUAUCACAGCCAGCUUUGAUGAGCUUAG
AAPP01016552.1/52617-52684       CAGCGCGUCGAAA-UGA-CU-G-UGACU--UAUG---CGUAUUUG--------AUGUCAUAUCACAGCCA-UUUUGACGAGUUUGG
AAPP01019563.1/1782-1715         UAACUCCUCAAAG--GG-CU-G-UGAAA--UGUU---GCCAUUAU-------CUACUCAUAUCACAGCCA-UUUUGAUGAGUUUCG
AAPP01019563.1/1637-1570         CAUGUCGUUAAAA-GGC-UU-G-UGACCU-UAUG---U----AUUUC-----GCAAUCAUAUCACAGCCA-UUUUGACGAGUUUGG
AAPU01011022.1/364143-364209     CAUGUCGUUAAAA-UGU-CU-G-UGACCG-UAU--------GUAUUC-----ACUAUCAUAUCACAGCCA-UUUUGACGAGUUUGG
AAZX01013101.1/19937-20004       UCGCCCGUCAGAG-UGG-UU-G-UGAUA--UGGU---G----CUAUU-----GAACGCAUAUCACAGCCAGCUUUGAUGUGCGUAA
AAPU01009688.1/35644-35576       UUGCGCGUCAAAU-UGA-CU-G-UGAGC--UAUG---UUUAUGAG-------AUUAUCAUAUCACAGCCA-UUUUGACGAGUUUGA
BAAB01090954.1/2518-2450         UCGCUCA-CAAAG-UGG-UU-G-UCG----UAUG---CGUUUUUACU-----UUGGCCAUAUCACAGCCAGCUUUGAUGAGCGAUG
AAJJ01001714.1/2663-2727         UCGCUCAUCAAC--UGG-AU-G-UGAAA--UGG---------AUUUG-----UAGCUCAUAUCACAGCCAGCUUUGAUGAGCGCUA
AASC02030054.1/11043-11110       CCUGACGUCAAGG-CGG-UU-G-UGAUG--UGGU---G----ACACC-----AUGAGCAUAUCACAGCCAGCUUUGAUGACAGGGA
AAGD02006756.1/79087-79015       AAGCCCGUCAAAG-UGG-CUCG-UGUUA--UGUU---GAAUCUUGAA-----GUAAUCAUAUCACAGCCAGCUUUGAUGUGCUUCC
AASC02030054.1/10795-10859       CAAGGCAUCAAAG-UGA-UU-G-UGAUG--UGU----------UUCA-----ACAAUCAUAUCACAGUCAGCUUUGAUGAGCUUGA
AADG06000036.1/25868-25935       CCGCUCA-CAAAG-UGG-UU-G-UGAUA--UGCU---GAUACGAG--------CGUUCAUAUCACAGCCAGCUUUGAUGAGCGUGG
AEKZ01001510.1/6921-6860         CGAUACAUCAAAU-UGG-UU-G-UGGAA--UGU------------UU-----CGAGUCAUAUCACAGCCA-UUUUGAUGAGCUUGG
ABEG02006312.1/20409-20483       AAGCACGUCAAAG-UGG-CGCG-UGUUA--UGUC---GGAAAUAUGAAA---AGGAUCAUAUCACAGCCAGCUUUGAUGUGCUUGA
AEKZ01001510.1/5353-5287         CCUCCCAUCAGAG-UGG-UU-G-UGA----UGUG---GUAACUUG--------GACUCGUAUCACAGCCAGCUUUGAUGAGCGGAA
AEKZ01001510.1/6572-6502         CCAAUCGUCAAAU-UGG-UU-G-UGGCG--UGUU---GCUUUUCU-A-----GAUUUCAUAUCACAGCCAUUUUUGACGAUUUGGA
#=GC SS_cons                     ::::<<<<<<<<<.<<<.<<.<.<<<--..<<<_...__________.....______>>>>>>>>>>>>->>>>>>>>>::::::
#=GC RF                          uaacuCgUCAAAg.uGG.cU.G.UGAaa..UGuu...guuauuuuuu.....uaaaUCaUAUCACAgCCaGcUUUGAcGaGcUugg
//
