# STOCKHOLM 1.0
#=GF ID IRE_I
#=GF AC RF00037
#=GF DE Iron response element I
#=GF AU Brown C
#=GF GA 34.0
#=GF NC 33.9
#=GF TC 34.0
#=GF PI IRE I; IRE; ferritin
#=GF SE Leipuviene, R. and Theil, E.C.
#=GF SS Published; PMID:17849083
#=GF TP Cis-reg;
#=GF BM cmbuild -F CM SEED
#=GF CB cmcalibrate --mpi CM
#=GF SM cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB
#=GF DR GO; 0010039; response to iron ion;
#=GF DR SO; 0001182; iron_responsive_element;
#=GF RN [1]
#=GF RM 3685996
#=GF RT Identification of the iron-responsive element for the translational
#=GF RT regulation of human ferritin mRNA.
#=GF RA Hentze MW, Caughman SW, Rouault TA, Barriocanal JG, Dancis A, Harford JB,
#=GF RA Klausner RD
#=GF RL Science. 1987;238:1570-1573.
#=GF RN [2]
#=GF RM 18160403
#=GF RT Ferritin L and H subunits are differentially regulated on a
#=GF RT post-transcriptional level.
#=GF RA Sammarco MC, Ditch S, Banerjee A, Grabczyk E
#=GF RL J Biol Chem. 2008;283:4578-4587.
#=GF RN [3]
#=GF RM 11903622
#=GF RT Repression of Manduca sexta ferritin synthesis by IRP1/IRE interaction.
#=GF RA Zhang D, Albert DW, Kohlhepp P, D-Pham DQ, Winzerling JJ
#=GF RL Insect Mol Biol. 2001;10:531-539.
#=GF RN [4]
#=GF RM 12429122
#=GF RT Structured RNA upstream of insect cap distal iron responsive elements
#=GF RT enhances iron regulatory protein-mediated control of translation.
#=GF RA Nichol H, Winzerling J
#=GF RL Insect Biochem Mol Biol. 2002;32:1699-1710.
#=GF RN [5]
#=GF RM 10070739
#=GF RT An atypical iron-responsive element (IRE) within crayfish ferritin mRNA
#=GF RT and an iron regulatory protein 1 (IRP1)-like protein from crayfish
#=GF RT hepatopancreas.
#=GF RA Huang TS, Melefors O, Lind MI, Soderhall K
#=GF RL Insect Biochem Mol Biol. 1999;29:1-9.
#=GF RN [6]
#=GF RM 17185597
#=GF RT Structure of dual function iron regulatory protein 1 complexed with
#=GF RT ferritin IRE-RNA.
#=GF RA Walden WE, Selezneva AI, Dupuy J, Volbeda A, Fontecilla-Camps JC, Theil
#=GF RA EC, Volz K
#=GF RL Science. 2006;314:1903-1908.
#=GF CC Iron respond element I 3D structure was reported in PDB 3SNP [6]
#=GF WK Iron_response_element
#=GF SQ 62

Y09188.1/1-35                               CU-G-UCUCUUGCUUCAACAGUGUUUGGACGGA-ACAG
M14211.1/193-227                            GG-G-UUUCCUGCUUCAACAGUGCUUGGACGG-AACCC
AY032659.1/108-140                          UC----GCC-UUCUGCACCAGUGUGUGUAAAGGCCUGA
AB099065.2/27-62                            CG-G-UUUCCUGCUUCAACAGUGCUUGAACGGNAACCG
AANN01127411.1/370-404                      CU-G-UUUCUUGCUUCAACAGUGUUUGGACGG-AACAG
AAIY01636926.1/362-328                      CU-G-UGUCCUGCUUCAACAGUGUUUGAACGGA-ACAG
ABGA01194773.1/10307-10273                  GG-G-CUUCCUGCUUCAACAGUGCUUGAACGGAA-CCC
ABRN01304445.1/359-393                      CU-G-UCUCUUGCUUCAACAGUGUUUGAACAGA-ACAG
AAPN01199084.1/201-236                      CG-G-UUUCCCGCUUCAACAGUGCUUGGACGGAAGCCG
AAQQ01605438.1/3746-3780                    CU-G-CUUCUUGCUUCAACAGUGUUUGGACGGAA-CAG
BAAE01241509.1/2881-2846                    GA-A-GUUCUUGCUUCAACAGUGUUUGAACGGAACUUC
D15071.1/10-45                              CG-G-UUUCCUGCUUCAACAGUGCUUGGACGGAACCCG
AB371410.1/64-99                            CG-G-UUUCUUGCUUCAACAGUGCUUGGACGGAAGCCG
ABDC01086142.1/996-1030                     CU-G-UCUCCGGCUUCAACAGUGUUUGGACGGA-ACAG
AAGV020889339.1/949-914                     UG-G-UUUCCUGCUUCAACAGUGCUUGAACGGAACCCA
AAWR02009010.1/38752-38718                  UG-G-UUUCCUGCUUCAACAGUGCUUGAACGG-AACCG
AB073371.1/2-37                             CG-G-UCUCCUGCUUCAACAGUGCUUGGACGGAGCCCG
ABVD01450449.1/988-1023                     UG-G-GUUCCUGCUUCAACAGUGCUUGAAUGGAACCCA
ABRT010002577.1/1339-1305                   CU-G-UCUCUUACUUCAACAGUGUUUGGAUGGA-ACAG
AF266195.1/11-46                            GA-G-AUUCUUGCUUCAACAGUGUUUGAACGGAAUUUC
ABQO010588503.1/1800-1767                   GG-G-UUUCCUGCUUCAACAGUGCUUGAACGG-A-CCC
ABRP01011077.1/2966-3000                    UU-G-UCUCUUGCUUCAACAGUGUUUGGACAGA-ACAG
ABRR01372656.1/429-395                      CU-G-UCUCUUGUUUCAACAGUGUUUGGACAGA-ACAG
AAFR03019774.1/239510-239545                GA-G-GUUCUUGCUUCAGCAGUGUUUGGACGGAACCUC
BT075303.1/10-45                            AG-G-UUACCUGCUUCAACAGUGCUUGAACGGCAACCU
BX934496.1/23-58                            CG-G-GUUCCUGCGUCAACAGUGCUUGGACGGAACCGG
AAPY01271888.1/1826-1792                    CG-G-UUUCCUGCAUCAACAGUGCUUGAACGG-AACCG
M55010.1/4-39                               AG-A-GUUCUUGCUUCAACAGUGUUUGAACGGAACCCU
AANG01554495.1/4632-4598                    CU-G-UCCCUUGCUUCAACAGUGUUUGGACAGA-ACAG
ABRO01415732.1/1669-1703                    CU-G-UGUCUUGCUUCAACAGUGUUUGGACAG-CACAC
AANH01004160.1/35803-35838                  GG-A-GUUCUUGCUUCAACAGUGUUUGAACGGAACUUU
AANU01126896.1/12416-12450                  CU-G-UAUCUUGCUUCAACAGUGUUUGGAUGGA-ACAG
BT047622.1/7-41                             -G-G-GUUCUUGCUUCAACAGUGAUUGAACGGAACUCC
ABRQ01098844.1/1724-1759                    CG-G-UGUCCUGCUUCAACAGUGCUUGAACGGAACCCG
AALT01281908.1/825-859                      CU-G-UCUCUUGCUUCAACAAUGUUUGGACGGA-GCAG
BC152596.1/22-57                            GA-G-GUUCUUGCUUCAACAGUGAUUGAACGGAACUUC
AAYZ01376712.1/735-701                      CU-G-UGUCUUGCUUCAACAGUGUUUGAAUGGA-ACAG
AF285177.1/2-35                             UG----UUCCUGCUUCAACAGUGCUUGGACGGAACCCG
AJ276505.2/120813-120779                    CU-G-UGUCUUGCUUCAACCGUGUUUGGACGGA-ACAG
BT073905.1/31-66                            GA-A-GUUCUUGCUUCAACAGUGAUUGAACGGAACUCC
DQ437112.1/26-59                            AG----UUCUUGCUUCAACAGUGAUUGAACGGAACACU
AAHY01029141.1/15302-15336                  CU-G-UGUCUUGCUUCAACAGUGUUUGGACGAA-ACAG
AF068225.2/1-36                             CG-G-UGUUUUGCUUCAACAGUGUUUGAACGAGCAUCG
DQ659631.1/11-46                            GU-U-GUUCUUGCUUCAACAGUGUUUGAACGGAACUUC
BC063337.1/26-62                            CGCA-GUUCUUGCUUCAACAGUGCUUGAACGGAACUCG
EF628371.1/43-77                            GA-G-GGUCUUGCUUCAACAGUGAUUGAACGGA-ACUC
ABAV01011851.1/25472-25507                  CC-G-UUUUGUGCUUCAACAGUGAUUGAACCGAAACAG
BT081799.1/21-57                            CC-GAGUUCUUGCUUCAACAGUGAUUGAACGGAGCCGG
ABQF01062964.1/539-575                      CC-GCGUUCUCGCUUCAACAGUGCUUGAACGGAACCGG
AAVX01381105.1/393-360                      UG----UUCUCGCUUCAACAGUGCUUGAACGGAACUGG
AY260753.1/1-34                             ---G-UUACCUGCUUCAACAGUGCUUGAACGGCAACCU
AY277900.1/12-47                            CG-A-UGUUAUGCUUCAACAGUGAUUGAACGAGCAUCG
AY550979.1/1-34                             UG----GUUUUGCUUCAACAGUGAUUGAACGAGCAUCG
AAGE02004546.1/6487-6454                    AG-G-UGUUUUGCUUCAACAUUGUUUGAACGA-C-CGU
AAWZ02023447.1/15493-15528                  UG-G-GUUCUUGCUUCAACAGUGUUUGAACGGGACCCG
AL592437.7/34848-34882                      CU-G-UUCCUUGCUUCAACAGUGUUUGGAUGG-AACAG
AAGU03011944.1/23235-23201                  CU-G-UUUCUUGCUUCAACAGUGCUUGGACGG-AGCAG
AAGW02057904.1/76866-76900                  CU-G-UGUCUUGCCUCAACAGUGUUUGAACGGA-ACAG
AAQR03095747.1/6073-6108                    CA-G-UUUCCUGCUUCAACAGUGCUUGGACGGAAACGG
AAHX01094585.1/10740-10774                  CU-G-UAUCUUGCUUCAACAGUGUUUGGACAGA-ACAG
AAPE02030929.1/24760-24794                  UG-G-UUUCCUGCUUCAACAGUGCUUGGACGG-AACCA
URS000080E11E_8355/1-30                     -----GUUCUUGCUUCAACAGUGUUUGAACGGAAC---
#=GR URS000080E11E_8355/1-30      3SNP_C_SS .....(((((.(.((((((...).)))))))))))...
#=GR URS000080E11E_8355/1-30      3SNP_D_SS .....(((((.(.((((((...).)))))))))))...
#=GC SS_cons                                <<.<.<<<<<-<-<<<<<<___>->>>>>>>>>>>>>>
#=GC RF                                     cg.G.uUUCUUGCUUCAACAGUGUUUGAACGGAAaCcg
//
