let-7 microRNA precursor clan

let-7 clan contains the families let-7 and mir-3596

This clan contains 2 families and the total number of sequence regions in the clan is 8,923.

Literature references

1. Kozomara A, Birgaoanu M, Griffiths-Jones S, Nucleic Acids Res. 2019;47:D155.: miRBase: from microRNA sequences to function. 30423142

Members

This clan contains the following 2 member families:

let-7 mir-3596

For those sequences which have a structure in the Protein DataBank, we generate a mapping between EMBL, PDB and Rfam coordinate systems. The table below shows the mapping between the Rfam families in this clan, the corresponding EMBL entries, and the region of the three-dimensional structures that are available for that sequence.

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family	Num. regions	Alignment
mir-3596 (RF04289)	229 (2.6%)	View
let-7 (RF00027)	8,694 (97.4%)	View