SNORA21 clan

The SNORA21 clan contains the RNA families SNORA21, snR10 and S_pombe_snR10. Homology between these families has been established in the published literature [1]. Researchers at the human snoRNA database (snoRNABase) have established that the following human and S. cerevisiae snoRNAs target modifications on orthologous positions of the ribosome: SNORA21 and snR10 [2].

This clan contains 3 families and the total number of sequence regions in the clan is 776.

Literature references

1. Li SG, Zhou H, Luo YP, Zhang P, Qu LH;, J Biol Chem. 2005;280:16446-16455.: Identification and functional analysis of 20 Box H/ACA small nucleolar RNAs (snoRNAs) from Schizosaccharomyces pombe. 15716270
2. Lestrade L, Weber MJ;, Nucleic Acids Res. 2006;34:D158-D162.: snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. 16381836

Members

This clan contains the following 3 member families:

SNORA21 snR10 S_pombe_snR10

External database links

External sites:

1: http://www-snorna.biotoul.fr/human_yeast/

This tool allows you to view the secondary structure images of two clan members side-by-side. Choose the family structures using the two drop-down menus below.

The table below shows the number of occurrences of each family throughout the sequence database. In brackets beside each number is the percentage of the total number of sequence hits for the clan that are represented by this family. The rightmost column provides a link to the alignments tab for each family.

Rfam family	Num. regions	Alignment
S_pombe_snR10 (RF01437)	2 (0.3%)	View
snR10 (RF01258)	86 (11.1%)	View
SNORA21 (RF00412)	688 (88.7%)	View