{"rfam": {"acc": "RF03545", "id": "Flavi_ISFV_CRE", "description": "Insect-specific Flavivirus 3' UTR cis-acting replication element (CRE)", "comment": "Flavi_ISFV_CRE is a Insect specific Flavivirus family. Flavivirus 3' UTR cis-acting replication element (CRE) plays a crucial role in the virus replication and is thought to be needed for the formation of a \"replication complex\" [1], it is composed of a small hairpin (sHP) and a larger structural element (3'SL). It has been shown that mutations in sHP are lethal for viruses [2]. CRE is involved in the 5'-3' UTR interaction of flaviviruses [3].", "curation": {"author": "Lamkiewicz K", "seed_source": "Lamkiewicz K", "num_seed": 16, "num_full": 13, "num_species": 27, "type": "Cis-reg;", "structure_source": "Predicted; LocARNA 2.0.0RC8"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 41.0, "trusted": 41.2, "noise": 40.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}