{"rfam": {"acc": "RF03540", "id": "Flavi_NKV_CRE", "description": "No-Known-Vector Flavivirus 3' UTR cis-acting replication element (CRE)", "comment": "Flavi_NKV_CRE is a Flavivirus family were the vector is not known. Flavivirus 3' UTR cis-acting replication element (CRE) plays a crucial role in the virus replication and is thought to be needed for the formation of a \"replication complex\" [1], it is composed of a small hairpin (sHP) and a larger structural element (3'SL). It has been shown that mutations in sHP are lethal for the virus [2]. CRE is involved in the 5'-3' UTR interation of flaviviruses [3]", "curation": {"author": "Lamkiewicz K", "seed_source": "Lamkiewicz K", "num_seed": 2, "num_full": 1, "num_species": 3, "type": "Cis-reg;", "structure_source": "Predicted; LocARNA 2.0.0RC8"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 50.0, "trusted": 51.7, "noise": 49.3}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}