{"rfam": {"acc": "RF03120", "id": "Sarbecovirus-5UTR", "description": "Sarbecovirus 5'UTR", "comment": "The 5' UTR of Sarbecovirus consists of 4 distinct stem-loops, namely SL1, SL2, SL3 and SL4. Further, there is a larger structure, SL5, present, which includes the first ORFs of the polyprotein. Note, that SL3 is typically present in SARS coronaviruses, but not necessarily conserved among other betacoronaviruses. SL1 is important for viral replication, most likely playing a role in the template-switch of viral subgenomic RNA transcription. SL2 is crucial for viral viability, however, the nucleotide sequence can be mutated and some residues, as long as the structure remains stable. SL4 is hypothesized to play a role in directing subgenomic RNA synthesis during viral replication.", "curation": {"author": "Lamkiewicz K", "seed_source": "Lamkiewicz K", "num_seed": 19, "num_full": 8, "num_species": 21, "type": "Cis-reg;", "structure_source": "Predicted;"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 50.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 150.0, "trusted": 229.1, "noise": 74.5}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00116", "id": "Coronavirus-5UTR"}}}