{"rfam": {"acc": "RF01909", "id": "CDKN2B-AS", "description": "CDKN2B antisense RNA 1 intronic convserved region", "comment": "CDKN2B-AS, also known as ANRIL (antisense non-coding RNA in the INK4 locus) is a long non-coding RNA consisting of 19 exons, spanning 126.3kb in the genome, and spliced product is a 3834bp RNA. It is located within the p15/CDKN2B-p16/CDKN2A-p14/ARF gene cluster, in the antisense direction. Single nucleotide polymorphisms (SNPs) which alter the expression of CDKN2B-AS are associated with many diseases, including coronary artery disease, diabetes and many cancers [1]. It binds to chromobox 7 (CBX7) within the polycomb repressive complex 1 and to SUZ12, a component of polycomb repression complex 2 and through these interactions is involved in transciptional repression [2,3].", "curation": {"author": "Eberhardt R", "seed_source": "Eberhardt R", "num_seed": 25, "num_full": 128, "num_species": 134, "type": "Gene; lncRNA;", "structure_source": "Predicted; RNAz; Eberhardt R"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 80.0, "trusted": 83.5, "noise": 64.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}