{"rfam": {"acc": "RF01831", "id": "THF", "description": "THF (Tetrahydrofolate) riboswitch aptamer", "comment": "Tetrahydrofolate (THF) riboswitch was first reported for Ames et al. [1] as an RNA motif in 5' untranslated (5'-UTR)regions of folate transport and biosynthesis genes in Firmicutes genomes. The structure of THF riboswitch has been reported in [2,3,4], it presents an inverted three-way junctional architecture. THF riboswitch presents a pseudoknot that joins P1-P2 and the loop of P3 and two THF binding. Tetrahydrofolate riboswitch structure is reported in PDB: 4LVV, 4LVW, 4LVX, 4LVY, 4LVZ, 4LW0 [4], 3SD3 [3], 3SUH, 3SUX, 3SUY [2], 6Q57 and 7KD1.", "curation": {"author": "Weinberg Z, Ames T, Ontiveros-Palacios N", "seed_source": "Published; PMID:20659680", "num_seed": 101, "num_full": 747, "num_species": 747, "type": "Cis-reg; riboswitch;", "structure_source": "Published; PMID:20659680"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 36.0, "trusted": 36.7, "noise": 34.8}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}