{"rfam": {"acc": "RF01812", "id": "Pxr", "description": "Pxr regulatory sRNA", "comment": "Downregulates genes responsible for the formation of fruiting bodies in Myxococcus xanthus, inhibiting the transition from growth to development in the presence of abundant nutrients.[1] Two-component system operon (histidine kinase gene and a \u00c3\u008f\u00c6\u201954 response regulator) is associated with production and processing of Pxr sRNA.[2] Folds into 3 steam loops. SL1 and SL 2 are highly conserved across mycobacteria and SL1 is necessary for the regulatory function. However, a conserved eight-base-pair segment of the variable SL3 is necessary for PxR accumulation and multicellular development.[3]", "curation": {"author": "Moore B", "seed_source": "Published; PMID:20489016", "num_seed": 2, "num_full": 7, "num_species": 9, "type": "Gene; sRNA;", "structure_source": "Published; PMID:20489016"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 80.0, "trusted": 84.9, "noise": 79.8}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}