{"rfam": {"acc": "RF01725", "id": "SAM-I-IV", "description": "SAM-I/IV (S-adenosyl methionine) riboswitch aptamer", "comment": "SAM-I-IV variant riboswitch is part of the clan CL00012 (SAM-I, SAM-IV and SAM-I-IV) which share a common SAM binding core. It is found upstream of a number of genes which code for proteins involved in methionine or cysteine biosynthesis. It has been found mostly in the order Actinomycetales [1]. PDB 4L81 and 4OQU has been reported for SAM-I-IV aptamer, which shows the SAM binding core and an alternative PK-2 subdomain shared with SAM-IV [3].", "curation": {"author": "Weinberg Z, Ontiveros-Palacios N", "seed_source": "Published; PMID:20230605;", "num_seed": 417, "num_full": 567, "num_species": 508, "type": "Cis-reg; riboswitch;", "structure_source": "Published; PMID:20230605;"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 41.1, "trusted": 41.1, "noise": 41.0}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00012", "id": "SAM"}}}