{"rfam": {"acc": "RF00634", "id": "SAM-IV", "description": "SAM (S-adenosyl methionine) riboswitch aptamer", "comment": "SAM-IV is a mRNA element that regulates gene expression via direct sensing of S-adenosylmethionine (SAM or AdoMet). SAM-IV riboswitches share conserved nucleotide positions with the previously described SAM-I riboswitches sequence analysis and molecular recognition experiments suggest that SAM-I and SAM-IV riboswitches share similar ligand binding sites, but have different scaffolds.", "curation": {"author": "Weinberg Z, Barrick JE", "seed_source": "Published; PMID:18369181", "num_seed": 40, "num_full": 2360, "num_species": 1305, "type": "Cis-reg; riboswitch;", "structure_source": "Published; PMID:18369181"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.61 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 38.0, "trusted": 38.2, "noise": 37.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00012", "id": "SAM"}}}