{"rfam": {"acc": "RF00622", "id": "CPEB3_ribozyme", "description": "Mammalian CPEB3 ribozyme", "comment": "The mammalian CPEB3 ribozyme is a self cleaving RNA located in the second intron of the CPEB3 gene which belongs to a family of genes regulating messenger RNA polyadenylation [1]. This ribozyme is highly conserved and found only in mammals [1]. The CPEB3 ribozyme is structurally and biochemically related to the human hepatitis delta virus (HDV) ribozyme (Rfam:RF00094) and the HDV ribozyme is proposed to have arisen from the human transcriptome [1]. There is currently only one other known self cleaving ribozyme in mammals, the CoTC motif (Rfam:RF00621)[2]. The structure of CPEB3 ribozyme has been reported in PDB 7QR3.", "curation": {"author": "Daub J, Ontiveros-Palacios N", "seed_source": "Published; PMID:16990549; INFERNAL", "num_seed": 14, "num_full": 5706, "num_species": 197, "type": "Gene; ribozyme;", "structure_source": "Published; PMID:16990549"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 35.0, "trusted": 35.0, "noise": 34.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}