{"rfam": {"acc": "RF00602", "id": "SCARNA21", "description": "Small Cajal body specific RNA 21", "comment": "scaRNAs are a specific class of small nuclear RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12 [1]. ACA68 (SCARNA21) is a member of the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis [2]. ACA68 is proposed to guide the pseudouridylation of residue U19 in U12 snRNA (Rfam:RF00007)[2].", "curation": {"author": "Daub J", "seed_source": "PMID:16373490", "num_seed": 24, "num_full": 278, "num_species": 138, "type": "Gene; snRNA; snoRNA; scaRNA;", "structure_source": "Predicted; RNAalifold; Daub J"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 25.65 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 60.0, "trusted": 60.0, "noise": 59.4}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}