{"rfam": {"acc": "RF00507", "id": "Corona_FSE", "description": "Coronavirus frameshifting stimulation element", "comment": "This family represents a conserved stem-loop found in Coronaviruses which can promote ribosomal frameshifting. This family interacts with a downstream region to form a pseudoknot structure, the region varies according to the virus but pseudoknot formation is known to stimulate frameshifting. In the classical situation a sequence 32nt downstream of the stem is complementary to part of the loop. In other Coronaviruses however, there is another stem loop structure around 150nt downstream that can interact with this family to form kissing stem loops and stimulate frameshifting [1]. The structure of coronavirus frameshifting has been reported in PDB 6XRZ and 7O7Z_AH [2,3]. Revised in 2020-2021 to expand the seed alignment.", "curation": {"author": "Moxon SJ, Nawrocki E, Ontiveros-Palacios N", "seed_source": "PMID:15680415", "num_seed": 51, "num_full": 76, "num_species": 94, "type": "Cis-reg; frameshift_element;", "structure_source": "Published; PMID:15680415"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 46.0, "trusted": 48.9, "noise": 37.3}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}