{"rfam": {"acc": "RF00480", "id": "HIV_FE", "description": "HIV Ribosomal frameshift signal", "comment": "This family represents the HIV Ribosomal frameshift signal. HIV uses a system called -1 ribosomal frameshifting to produce the required ratio of Gag and Gag-Pol polyproteins. The stem-loop structure of the frameshift signal is thought to impede the ribosome and cause slippage in the 5' direction, this causes the -1 frameshift and translation then continues in the new frame [1]. The structure of HIV Ribosomal framershift signal has been reproted in PDB: 1Z2J, 2L94, 6VWL, 6VWM and 6VWN [2, 3,4].", "curation": {"author": "Moxon SJ, Ontiveros-Palacios N", "seed_source": "PMID:14747573", "num_seed": 147, "num_full": 29, "num_species": 18, "type": "Cis-reg; frameshift_element;", "structure_source": "Published; PMID:14747573"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 45.0, "trusted": 47.4, "noise": 44.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}