{"rfam": {"acc": "RF00455", "id": "mir-15", "description": "mir-15 microRNA precursor family", "comment": "This family represents the related mir-15a and mir-15b sequences. In humans miR-15a and miR-16 are clustered within 0.5 kb at 13q14. This region has been shown to be deleted in more than half of B cell chronic lymphocytic leukaemias (CLL). Both miR-15a and miR-16 are deleted or down-regulated in more than two thirds of CLL cases [2]. The mature sequence is excised from the 5' arm of the hairpin. The family represents the microRNA (miRNA) precursor mir-125 imported from miRBase [3].", "curation": {"author": "Griffiths-Jones SR", "seed_source": "Griffiths-Jones SR", "num_seed": 164, "num_full": 2045, "num_species": 649, "type": "Gene; miRNA;", "structure_source": "Predicted; RNAalifold"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 57.3, "trusted": 57.3, "noise": 57.2}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00085", "id": "mir-15"}}}