{"rfam": {"acc": "RF00454", "id": "p27_CRE", "description": "p27 cis-regulatory element", "comment": "This family represents a structured G/C rich element located in the 5' UTR of p27 mRNA. This element contributes to cell-cycle regulated translation and when deleted leads to a 50% drop in regulation. The element is thought to be able to form several different structures with similar free energy. It has been suggested that proteins may only bind to a specific structure thus conformational changes could regulate translation [1].", "curation": {"author": "Moxon SJ", "seed_source": "PMID:12837699, INFERNAL", "num_seed": 12, "num_full": 110, "num_species": 110, "type": "Cis-reg;", "structure_source": "Predicted; PFOLD; Moxon SJ"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 27.34 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 42.0, "trusted": 42.8, "noise": 41.2}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}