{"rfam": {"acc": "RF00406", "id": "SNORA42", "description": "Small nucleolar RNA SNORA42/SNORA80 family", "comment": "The members of this family belong to the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. Human ACA42 (SNORA42) was cloned from HeLa cells by immunoprecipitation with anti-GAR1 antibody [1]. Its is predicted to guide the pseudouridylation of residues U109 and U572 of 18S rRNA [3]. ACA42 shares the same host gene with ACA26, ACA46, ACA50 [1]. This family also includes mammalian snoRNA ACA67 (SNORA80) which was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis [2]. ACA67 is proposed to guide the pseudouridylation of the same 18S rRNA residues as ACA42 [3].", "curation": {"author": "Moxon SJ, Daub J", "seed_source": "PMID:1637349", "num_seed": 21, "num_full": 1535, "num_species": 183, "type": "Gene; snRNA; snoRNA; HACA-box;", "structure_source": "Predicted; RNAalifold"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 18.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 70.0, "trusted": 70.0, "noise": 69.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}