{"rfam": {"acc": "RF00374", "id": "Gammaretro_CES", "description": "Gammaretrovirus core encapsidation signal", "comment": "This family represents the Gammaretrovirus (mammalian type C retrovirus) core encapsidation signal and related sequences. The Moloney murine leukaemia virus (MMLV) core encapsidation signal is know to be essential for stable dimerisation and efficient genome packaging during virus assembly [1]. Dimerisation of the viral RNA genomes is proposed to act as an RNA conformational switch which exposes conserved UCUG elements and enables efficient genome encapsidation [2]. The structure of Gammaretrovirus core encapsidation signal has been reported in PDB: 1S9S, 1U6P, 2L1F [1,2,3].", "curation": {"author": "Moxon SJ, Daub J, Ontiveros-Palacios N", "seed_source": "PMID:15003457", "num_seed": 25, "num_full": 81, "num_species": 15, "type": "Cis-reg;", "structure_source": "Published; PMID:15003457"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 93.0, "trusted": 93.3, "noise": 88.4}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}