{"rfam": {"acc": "RF00259", "id": "IFN_gamma", "description": "Interferon gamma 5' UTR regulatory element", "comment": "This family represents a pseudoknot containing stem-loop structure found in the 5' UTR of interferon (IFN) gamma mRNA. This structure is thought to be involved in translational regulation and the pseudoknot has been found to activate PKR which is known to be a translational inhibitor. Mutations in the pseudoknot structure have been found to reduce PKR activation and increase the translation of IFN-gamma [1].", "curation": {"author": "Moxon SJ", "seed_source": "PMID:11832212", "num_seed": 5, "num_full": 135, "num_species": 125, "type": "Cis-reg;", "structure_source": "Published; PMID:11832212"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 20.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 40.0, "trusted": 40.8, "noise": 39.8}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}