{"rfam": {"acc": "RF00250", "id": "mir-TAR", "description": "Trans-activation response element (TAR)", "comment": "This family represents the HIV trans-activation response (TAR) element which is known to be required for the trans-activation of the viral promoter and for virus replication. The TAR hairpin acts as a binding site for the Tat protein and this interaction stimulates the activity of the long terminal repeat promoter [1]. Further experiments have shown that TAR acts as a miRNA that protects against apoptosis [2,3].", "curation": {"author": "Moxon SJ", "seed_source": "PMID:12882959", "num_seed": 45, "num_full": 48, "num_species": 20, "type": "Gene; miRNA;", "structure_source": "Published; PMID:12882959"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 40.0, "trusted": 45.9, "noise": 37.2}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}