{"rfam": {"acc": "RF00210", "id": "IRES_Picorna_2", "description": "Aphthovirus internal ribosome entry site (IRES)", "comment": "This family represents the internal ribosome entry site (IRES) of the the aphthoviruses. IRES elements allow cap and end-independent translation of mRNA in the host cell. The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for eIF4F [2].", "curation": {"author": "Moxon SJ", "seed_source": "PMID:14561883", "num_seed": 92, "num_full": 12, "num_species": 29, "type": "Cis-reg; IRES;", "structure_source": "Published; PMID:14561883"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 16.93 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 50.0, "trusted": 61.3, "noise": 49.1}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}