{"rfam": {"acc": "RF00185", "id": "Flavi_CRE", "description": "Flavivirus 3' UTR cis-acting replication element (CRE)", "comment": "This family represents the Flavivirus 3'-SL cis-acting replication element (CRE). The family is thought to play a crucial role in replication and is thought to be needed for the formation of a \"replication complex\" [1]. Although evidence has been presented for an existence of a pseudoknot structure in this RNA [2], it does not appear to be well conserved across flaviviruses. Deletions of the 3' UTR of flaviviruses have been shown to be lethal for infectious clones.", "curation": {"author": "Bateman A, Moxon SJ, Weinberg Z", "seed_source": "Bateman A, Moxon SJ, Weinberg Z", "num_seed": 84, "num_full": 6, "num_species": 21, "type": "Cis-reg;", "structure_source": "Published; PMID:9696848; Bateman A, Moxon SJ, Weinberg Z"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 24.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 42.0, "trusted": 42.2, "noise": 40.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}