{"rfam": {"acc": "RF00168", "id": "Lysine", "description": "Lysine riboswitch aptamer", "comment": "Riboswitches are metabolite binding domains within certain messenger RNAs that serve as precision sensors for their corresponding targets. Allosteric rearrangement of mRNA structure is mediated by ligand binding, and this results in modulation of gene expression. This family includes riboswitches that sense lysine [1] in a number of genes involved in lysine metabolism, including lysC [3].", "curation": {"author": "Wickiser JK, Barrick JE, Breaker RR", "seed_source": "Wickiser JK, Barrick JE", "num_seed": 47, "num_full": 3224, "num_species": 1923, "type": "Cis-reg; riboswitch;", "structure_source": "Published; PMID:12787499"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 21.63 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 30.0, "trusted": 30.2, "noise": 29.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}