{"rfam": {"acc": "RF00151", "id": "SNORD58", "description": "Small nucleolar RNA SNORD58", "comment": "snoRNA U58 is found in introns 1, 3 and 6 of the ribosomal protein RPL17 gene in humans. U58 is a member of the C/D class of snoRNA which contain C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. U58A and U58B are predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit on position G4198 [2]. Although the selection of the target nucleotide requires the antisense element and the conserved box D or D' of the snoRNA, the methyltransferase activity is supposed to reside in one of the protein components [1].", "curation": {"author": "Moxon SJ, Daub J", "seed_source": "Griffiths-Jones SR", "num_seed": 33, "num_full": 2484, "num_species": 680, "type": "Gene; snRNA; snoRNA; CD-box;", "structure_source": "Predicted; PFOLD"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 26.89 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 42.0, "trusted": 42.0, "noise": 41.8}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00064", "id": "SNORD58"}}}