{"rfam": {"acc": "RF00147", "id": "SNORD34", "description": "Small nucleolar RNA SNORD34", "comment": "snoRNA U34 is found in intron 5 of the ribosomal protein L13a gene in humans. U34 is a member of the C/D class of snoRNA which contain C (UGAUGA) and D (CUGA) box motifs, and functions in directing site-specific 2'-O-methylation of 25S rRNAs. Although the selection of the target nucleotide requires the antisense element and the conserved box D or D' of the snoRNA, the methyltransferase activity is thought to reside in one of the protein components [1]. U34 snoRNA has homologues in mouse, Arabidopsis (annotated as snoR4) and in several copies in rice (alternatively named snoZ181) [2]. This family also contains a putative homologue in Drosophila (Griffiths-Jones SR, pers. obs.).", "curation": {"author": "Moxon SJ", "seed_source": "Griffiths-Jones SR", "num_seed": 14, "num_full": 1319, "num_species": 583, "type": "Gene; snRNA; snoRNA; CD-box;", "structure_source": "Predicted; PFOLD, Griffiths-Jones SR"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 26.84 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 38.0, "trusted": 38.0, "noise": 37.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00055", "id": "SNORD34"}}}