{"rfam": {"acc": "RF00133", "id": "SNORD33", "description": "Small nucleolar RNA Z195/SNORD33/SNORD32 family", "comment": "Members of this family belong to the C/D box class of small nucleolar RNA which contain C (UGAUGA) and D (CUGA) box motifs. This family includes plant snoRNA Z195, human snoRNAs SNORD33 (U33) and SNORD32 (U32). snoRNA U33 is found in intron 4 of the ribosomal protein L13a gene in humans and is also present in mice. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. Although the selection of the target nucleotide requires the antisense element and the conserved box D or D' of the snoRNA, the methyltransferase activity is supposed to reside in one of the protein components [3].", "curation": {"author": "Moxon SJ, Daub J", "seed_source": "Griffiths-Jones SR, Daub J, INFERNAL", "num_seed": 72, "num_full": 1868, "num_species": 712, "type": "Gene; snRNA; snoRNA; CD-box;", "structure_source": "Predicted; PFOLD; Daub J"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 28.26 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 44.0, "trusted": 44.0, "noise": 43.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00054", "id": "SNORD33"}}}