{"rfam": {"acc": "RF00090", "id": "SNORA74", "description": "Small nucleolar RNA SNORA74", "comment": "U19 belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs [1]. Targets may include ribosomal and spliceosomal RNAs but the exact functions of many snoRNAs, including U19, are not confirmed. Co-precipitation of U19 snoRNA with RNase MRP RNA suggests that U19 may be involved in pre-rRNA processing [2].", "curation": {"author": "Griffiths-Jones SR", "seed_source": "Griffiths-Jones SR, INFERNAL", "num_seed": 24, "num_full": 1348, "num_species": 628, "type": "Gene; snRNA; snoRNA; HACA-box;", "structure_source": "Predicted; PFOLD; Griffiths-Jones SR"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 19.50 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 71.0, "trusted": 71.0, "noise": 70.7}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00043", "id": "SNORA74"}}}