{"rfam": {"acc": "RF00072", "id": "SNORA75", "description": "Small nucleolar RNA SNORA75", "comment": "U23 belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs [3]. Targets include ribosomal and spliceosomal RNAs as well as the Trypanosoma spliced leader RNA (SL RNA) as possibly other, still unknown cellular RNAs [3]. U23 can direct the pseudouridylation of U97 in human 18S rRNA (Bachellerie JP, Ganot, P unpublished data). U23 is encoded within intron 12 of the nucleolin gene in human, mouse, rat chicken, and Xenopus laevis.", "curation": {"author": "Bachellerie JP, Griffiths-Jones SR", "seed_source": "Griffiths-Jones SR", "num_seed": 6, "num_full": 414, "num_species": 310, "type": "Gene; snRNA; snoRNA; HACA-box;", "structure_source": "Predicted; PFOLD; Griffiths-Jones SR"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 34.61 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 80.0, "trusted": 80.0, "noise": 79.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}