{"rfam": {"acc": "RF00047", "id": "mir-2", "description": "mir-2 microRNA precursor family", "comment": "This family represents the microRNA (miRNA) precursors mir-2 and mir-13 (MIPF:MIPF0000049). mir-2 has now been predicted or experimentally confirmed in a wide range of species. The miRNAs are transcribed as ~70nt precursors (modelled here) and subsequently processed by the Dicer enzyme to give a ~22nt product. In this case the mature sequence comes from the 3' arm of the precursor. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA. The involvement of Dicer in miRNA processing suggests a relationship with the phenomenon of RNA interference. miRNAs are numbered based on the mature sequence. This family also contains the mir-13 precursor which, despite giving rise to a distinct mature sequence appears to be related in sequence.", "curation": {"author": "Griffiths-Jones SR, Daub J", "seed_source": "Griffiths-Jones SR", "num_seed": 56, "num_full": 918, "num_species": 280, "type": "Gene; miRNA;", "structure_source": "Predicted; PFOLD"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 30.00 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 45.5, "trusted": 45.5, "noise": 45.4}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": null, "id": null}}}