{"rfam": {"acc": "RF00045", "id": "SNORA73", "description": "Small nucleolar RNA SNORA73 family", "comment": "U17 (SNORA73A and SNORA73B) also known as E1 belongs to the H/ACA class of small nucleolar RNAs (snoRNAs). Vertebrate U17 is intron-encoded and ranges in length from 200-230 nucleotides, longer than most snoRNAs. It is one of the most abundant snoRNAs in human cells and is essential for the cleavage of pre-rRNA within the 5' external transcribed spacer (ETS) [1]. This cleavage leads to the formation of 18S rRNA. Regions of the U17 RNA are complementary to rRNA and act as guides for RNA/RNA interactions, although these regions do not seem to be well conserved between organisms [2].", "curation": {"author": "Griffiths-Jones SR", "seed_source": "Griffiths-Jones SR; Cervelli et al, PMID:11821910", "num_seed": 66, "num_full": 2326, "num_species": 660, "type": "Gene; snRNA; snoRNA; HACA-box;", "structure_source": "Published; PMID:11821910"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 22.54 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 74.0, "trusted": 74.0, "noise": 73.9}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00078", "id": "snR30-U17"}}}