{"rfam": {"acc": "RF00007", "id": "U12", "description": "U12 minor spliceosomal RNA", "comment": "The U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. Although the U12 sequence is very divergent from that of U2 (Rfam:RF00004), the two are functionally analogous [2]. The predicted secondary structure of U12 RNA is published (see for example, PMID:10199569), but the alternative single hairpin in the 3' end shown here seems to better match the alignment of divergent Drosophila and Arabidopsis sequences.", "curation": {"author": "Griffiths-Jones S, Mifsud W, Gardner PP", "seed_source": "Shukla GC and Padgett RA, PMID:10199569; PMID:18390578", "num_seed": 62, "num_full": 2106, "num_species": 1170, "type": "Gene; snRNA; splicing;", "structure_source": "Predicted; Griffiths-Jones S"}, "cm": {"build_command": "cmbuild -F CM SEED", "calibrate_command": "cmcalibrate --mpi CM", "search_command": "cmsearch --cpu 4 --verbose --nohmmonly -T 27.53 -Z 2958934 CM SEQDB", "cutoffs": {"gathering": 53.0, "trusted": 53.0, "noise": 52.8}}, "release": {"date": "2026-01-16", "number": "15.1"}, "clan": {"acc": "CL00006", "id": "U2"}}}